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Sepsis Collaborative

Every year in the UK there are 150,000 cases of sepsis, resulting in a staggering 44,000 deaths – more than bowel, breast and colon cancer combined.

Sepsis is the biggest direct cause of death in UK pregnancies and affects about 10,000 children every year in the UK.

Sepsis is a life threatening condition that arises when the body’s response to an infection injures its own tissues and organs. Sepsis leads to shock, multiple organ failure and death especially if not recognized early and treated promptly.

Our Sepsis Collaborative is working on improving sepsis care for patients across the West of England as part of the Safer Care through Early Warning Scores project.

Find out more about sepsis in this clip from BBC2’s Trust Me I’m a Doctor…

To find out more about symptoms of sepsis in children under 5 visit NHS Choices.   For a support leaflet for parents.

Yeovil District Hospital and South West Ambulance Service Foundation Trust have produced a really good short video to explain the sepsis 6 in 90 secs.



The UK Sepsis Trust has developed a range of clinical toolkits to support clinical areas in the improvement of sepsis care – click here for toolkits for out of hours, community services, ambulance, GPs, ED/AMU and Acute Hospital-inpatients.

The Health Innovation Network (HIN) has been working in partnership with NHS England and the ASK SNIFF Safety Netting Collaborative to produce the “Spotting the signs of Sepsis” film series now on NHS Choices.

The clinical content is based on the Public Health parental awareness campaign materials that were developed in collaboration with the UK Sepsis Trust and launched in December 2016.

For Emergency Department clinicians wanting more information on sepsis, please click here.

For Primary Care clinicians wanting more information on sepsis, please click here.

Latest Guidance


Sepsis – a simple, pragmatics, evidence-based approach to detection, collaboration and measurement.

By Dr Matt Inda-Kim, Consultant Acute Physician at Hampshire Hospitals, NHS(E) National Clinical Advisor on Sepsis, Co-Chair of the National AHSN Sepsis Cluster, Clinical Lead for Sepsis and Deterioration at Wessex Patient Safety Collaborative.


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Learning and sharing

The West of England AHSN is part of the AHSN sepsis cluster, working on the Sepsis Action Plan published by NHS England in 2015.


If you would like to get involved in our Sepsis Collaborative, then please contact Nathalie Delaney at

To be kept up-to-date on the work of the Patient Safety Collaborative and the West of England AHSN in general, why not sign up to our monthly e-newsletter?

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