Launched in April 2020, PERIPrem (Perinatal Excellence to Reduce Injury in Premature Birth) is a perinatal care bundle to improve the outcomes for premature babies across the West and South West AHSN regions. The bundle consists of eleven interventions that demonstrate a significant impact on brain injury and mortality rates amongst babies born prematurely.

Links to each of the bundle elements and resources for implementation can be found at the bottom of this page.

View the PERIPrem baby and clinical passports.


In August 2022, an independent evaluation was published in the British Medical Journal Open Quality. It indicated 26% more mothers and babies born prematurely across the South West received the care interventions they were eligible for between July 2020 and June 2021, compared to before PERIPrem started. Explore a summary graphic of the PERIPrem evaluation.

In July 2022 PERIPrem was shortlisted as best national/regional project at the BAPM Gopi Menon Awards.

Official PERIPrem resources have received Neonatal Nurses Association (NNA) endorsement. They were also recommended in the April 2022 GIRFT Neonatology Report (see pages 10 and 66).

At the 2021 HSJ Patient Safety Awards, PERIPrem was highly commended as the Patient Safety Pilot of the Year. PERIPrem was also shortlisted for Provider Collaboration of the Year at the 2021 HSJ Awards. Read more about PERIPrem’s impact in our case study.

Watch our short video where parents of premature babies discuss how their births were affected by PERIPrem.

The National Neonatal Audit Programme’s (NNAP) latest report, shows units across the South West achieved, on average, the:

  • highest rate of delayed cord clamping (by over 21%),
  • third lowest rates of mortality to discharge,
  • the second lowest rates of necrotising enterocolitis,
  • alongside the fourth highest administration levels of magnesium sulphate (MgSO4) across England.

PERIPrem case studies were published in April 2022 by NHS Confederation and in July 2022 in the National Child Mortality Database thematic report (pages 21-22).

But what is PERIPrem?

Watch our short explainer video:

PERIPrem is not just about implementing a care bundle. It is about forging a new way of working, where clinicians from obstetrics, midwifery and neonatal join together to drive forward and revolutionise care for pre term babies. Read more about the project.

As of April 2021, PERIPrem became part of the AHSN’s local activity to deliver the ambitions of the NHS England Maternal and Neonatal Safety Improvement Programme.

Resources to implement PERIPrem

Our resources page contains all of the current clinical tools and documents that will support teams on a PERIPrem journey. This includes a number of documents in both English and other languages that are designed to help inform and fully involve parents in the care of their preterm baby.

Our useful materials page  contains general resources and playlists of key videos.

The PERIPrem bundle elements