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PReCePT stands for the Prevention of Cerebral Palsy in PreTerm Labour. This initiative has been designed to help reduce cerebral palsy in babies by administering magnesium sulphate (MgSO4) to mothers during preterm labour. The treatment costs from £1 per individual dose.

The PReCePT initiative has so far prevented around seven cases of cerebral palsy in the West of England, representing potential lifetime healthcare savings in the region of £5 million and substantially more when including loss of productivity and social care costs over a lifetime.

The PReCePT initiative was developed by the West of England AHSN in collaboration with University Hospitals Bristol NHS Foundation Trust, and involved both patients and staff.


Watch our videos to find out more:

The PReCePT Programme – national adoption and spread of PReCePT

Following the successful roll out of PReCePT to all five acute trusts in the West of England in 2016, PReCePT is one of the seven local AHSN programmes to have been selected for national adoption and spread across the AHSN Network during 2018-2020, funded by NHS England. We will lead this programme.

This work will bring together the 15 AHSNs and the aligned drivers of the Maternal and Neonatal Health Safety Collaborative (MNHSC) and the national Patient Safety Collaboratives (PSCs). Together, we aim to achieve 85% uptake of administration of MgSO4 to preterm babies in maternity units across England, from an average baseline of 43% (2016 NNAP data). We have a stretch target of 95% by 2020.

Between 4,000 and 5,000 babies are born before 30 weeks’ gestation in England per year and stand to benefit from full national roll out of the PReCePT Programme. Successful scaling up of PReCePT is likely to prevent several hundred cases of cerebral palsy per year, based on very strong research evidence.


The PReCePT Study: Scaling-Up funding

The project is now benefiting from £0.5 million in ‘Scaling Up’ funding from the Health Foundation. This will fund an evaluation to study the effectiveness of two different Quality Improvement approaches in implementing the intervention across a subset of maternity units. Read more here.


Other PReCePT resources

In March 2018, we held a webinar to share the next steps for the PReCePT initiative. Find the webinar resources here.

Read the PReCePT case study here.